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You frequently get involved in conversations about science and faith. You may have also composed several textbooks on the subject. Don’t you feel that at some point We are going to know every thing Which God’s function might be above?
Multicolor imaging from the bacterial nucleoid and mobile division proteins with blue, orange, and in the vicinity of-infrared fluorescent proteins
Considering the fact that 2000, Dekker has shifted the key aim of his function in direction of biophysics where by he research the Houses of one biomolecules and cells utilizing the tools of nanotechnology. This variation of subject was pushed by his fascination for the outstanding operating of Organic molecular buildings, together with via the lengthy-phrase point of view a large number of attention-grabbing discoveries may be anticipated On this subject.[five] Latest strains of investigate in his biophysics team are in the areas of:[6]
This yielded a breakthrough. Inside only a few months, we ended up capable of evaluate transport by a person one-walled carbon nanotube. According to small-temperature experiments by an excellent PhD university student in my group, Sander Tans (now a valued colleague and professor at Delft College of Technologies by having an active investigation lab at AMOLF in Amsterdam), we showed that carbon nanotubes have been legitimate quantum wires with really very long (micrometres) electronic coherence lengths — confirming theoretical predictions of metallic conduct.
Experimental phase diagram of negatively supercoiled DNA measured by magnetic tweezers and fluorescence,
What distinguishes biology from chemistry is the fact that these factors with each other make up a dwelling program. The trick of mentioned everyday living, I think, lies while in the interactions, the interaction of Individuals molecules. The massive issue about the origin of daily life remains unanswered. How did we ever evolve from uncomplicated molecules into the really complex techniques we see now? We have no idea. I would like to operate on These types of large, open thoughts.’
2011, first in vitro measurements of transportation throughout an individual biomimetic nuclear pore sophisticated; advancement of multiplexed magnetic tweezers for kilo-molecule experiments; and settled the system of homology recognition in DNA homologous recombination
The rotors harness Electrical power from the nanoscale water and ion move that is certainly generated by a static chemical or electrochemical opportunity gradient while in the nanopore, which can be established by way of a salt gradient or applied voltage, respectively. These synthetic nanoengines self-organize and work autonomously in physiological conditions, suggesting solutions to constructing Electrical power-transducing motors at nanoscale interfaces.
There was one particular challenge nevertheless — we didn't notice any measurable electrical conduction from The one polymer molecules. We concluded that at The one-molecule amount, conducting polymers were being actually not this kind of fantastic conductors, which was fairly disappointing. We Hence broadened our check out to try https://www.ceesdekker.net to discover a lot more promising molecules.
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1999, 1st measurement of the wavefunction of single molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive evidence for just a new Luttinger description of interacting electrons in nanotubes
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of just one wire bridging two electrodes
Sound-state nanopores have confirmed to be a surprisingly multipurpose probe for single-molecule Evaluation of DNA. I will explain many of our current results – especially DNA knots – and also our initiatives to increase the abilities of sound-state nanopores even further more, from the route of single-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.